Cardiovascular Health

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09/24/2024

A-Fib, or Atrial Fibrillation has become more prevelant over the past 5-10 years. A large percentage of individuals live with it, as opposed to having a cardioversion or ablation procedure, where in most cases they are unaware if they are in this abnormal rythm or not. However, its important to recognize certain symptoms, as to when to seek treatment. As far as prophylaxis and preventative measures, its common for healthcare practitioners to prescribe anti-coagulants / blood thinners to prevent the formation of a thrombus (blood clot) inside one of the chambers of the heart. If formed on the right side of the heart, the result can be for it to travel to the lungs and cause a pulmonary embolism. If on the left side there is the risk of stroke, or a blood clot traveling down the aorta and causing a problem with blood flow to an organ or a lower extremity. Anti-coagulants / blood thinners have side effects, as opposed to Curcumin in Turmeric which has a healthy blood thinning profile, along with significant health benefits on all body systems. No one case is the same, and sometimes we recommend different protocols. However, Curcu-Meric 975mg is extremely beneficial in individuals with A-Fib, not only for the healthy blood thinning effects, but also for its cardiovascular benefits.

Curcu-Meric 975mg

8/16/2024

Blood Clots have been an important topic in the medical literature over the past few years. Coagulation of our blood, and regulation of how thin and thick it is involves much more than the quantity and health of our platelets. As can be seen from the 2 diagrams below, the blood clotting cascade involves many factors / cofactors and proteins to function properly.

In referencing the above diagrams we can see blood clotting involves much more than platelets. 90-95% of medical complications arise from excessive blood clotting as opposed to the blood being too thin. Throughout the majority of our life it becomes healthy to keep your blood mildly thin to prevent blood clots and improve circulation for the delivery of oxygen and micronutrients / minerals. In the elderly is where it becomes a double edge sword for the following reason. The elderly population has more fragile blood vessels, and 2 areas of concern are the cerebral (Brain) circulation and the Intestinal tract. These 2 areas in the elderly are at increased risk for bleeding due to several factors, and can cause bleeding, resulting in Anemia from Intestinal tract blood loss, and rare but potential bleeding in the brain, known as a hemmorhagic stroke. However, 90% of strokes are thrombotic from a blood clot and only 10% are hemmorhagic. Many factors come to play when assesing risk and benefit, however, even in the elderly keeping the blood mildly thin has more benefit than risk due to different degree of coronary artery blockage, and other areas such as the carotid arteries and arteries of the lower extremities. That was a simplified overview, as we will discuss many more scenarios pertaining to this topic. Thus, Curcumin / Turmeric- Our Curcu-Meric 975mg Capsule is a great option to lower whole-body inflammation, optimize the immune system, improve circulation, and mildly thin the blood to prevent blood clots.

8/15/2024

The above image a great synopsis of how certain meds affect the kidney. NSAIDS inhinit prostaglandins which constricts / narrows blood entering the kidney filtration system. NSAIDS will subsequently slow kidney filtration, and send a message to the cardiovascular system that it is not receiving enough blood to filter, causing a constriction in ALL vessels in the body and subsequently increased blood pressure. On the other end of the kidney filtration system (Bowmans Capsule)- The Blood leaving is affected by ACE Inhibitors and ARB’s (Angiotensin Receptor Blockers) where they dilate the vessel with blood leaving the filtration system, and thus make the body sense excess blood flow in the kidney and cause a reflex relaxation of the rest of the vessels in the Cardiovascular system thus lowering blood pressure. Thus, ACE Inhibitors and ARB’s lower blood pressure, and have a protective effect on the Kidney, especially in Diabetics, which is why diabetics are routinely prescribed these meds. If the Individual with Diabetes has normal blood pressure, in many instances in those with long standing diabetes with mild renal insufficiency they are prescribed low dose ACE Inhibitors. LOWERING YOUR INFLAMMATION has significant positive impact on the kidneys at these same areas: Afferent and Efferent Arterioles along with Bowman’s Capsule, accomplishing protection from Agents such as NSAIDS, and maintaining proper blood flow throgh Bowmans capsule for proper kidney filtration and proper feedback to the rest of the cardiovascular sytem, maintaining normal blood pressure and proper circulation to ALL organs.

Images will be posted weekly, and below each we will discuss briefly a medical / health topic related to the image. If you do not see the brief paragraph following the image, please check back in 7 days. Dr. Miller will post his medical / health topic related to that specific image above.

Cardiovascular disease remains the most prevelant cause of morbidity and mortality, and one of the most preventable disorders with proper nutrition, exercise and LOWERING YOUR INFLAMMATION !!!

Cholesterol is only ONE of many factors impacting your arterial health. Many factors impact the development of arteriosclerosis, and the common pathway is Oxidative Stress (chronic inflammation) at the inner surface of the artery, on the endothelial surface

Aspirin was the “go to” agent in the past to prevent arteriosclerosis, WHY? because of its anti-inflammatory effects, and blood thinning (anti-platelet) effects. Aspirin has fallen out of favor due to several reasons. One being the unacceptable elevated risk of hemmorhagic stroke in those taking it daily for primary prevention of cardiovascular disease. Secondly, Intestinal tract mucosal disruption and Intestinal tract bleeding was another reason it fell out of favor, along with liver health problems, and low platelets (Thrombocytopenia).

Next Newsletter will discuss the LDL / Cholesterol Dilemma – The medical community is analyzing whether or not our lowering of cholesterol has gone to far, and whether or not the thresholds of normal should be raised. Cholesterol is protective to our cell membranes, and our Nervous System. The excessive lowering may be contributing to increased prevelance of Neuro-degenerative disorders, autoimmune disorders, and other disorders. Lowering cholesterol is good, however, too low may not be good.

Plant-based compounds, especially Curcumin / Turmeric have significant benefit over and above aspirin, for Cardiovascular Disease Prevention, without the adverse effects.

There is lots of info to cover regarding Calcium Metabolism and Arteriosclerosis. Coronary Calcium Scans (Special CT scan of the heart) has become a popular test to determine calcium build-up in the coronary arteries. There is much to interpret regarding these results, and I will expand on this more in the next newsletter.

First, we can’t assume with great accuracy the degree of coronary artery obstruction based upon the Calcium score alone. Yes there is a direct corrolation between the two, however, for example, an individual can have a moderately high calcium score of 160, and only have 15% occlusion of the coronary artery, whereas someone else can have the same calcium score, and have 30% occlusion of the coronary artery.

WHY?

If you refer to the above image, in the artery labeled calcified artery, the area pointed to labeled plaque which is yellow, is the soft plaque which is the first thing to develop from chronic inflammation (oxidative stress) from many causes, cholesterol, diabetes, hypertension, autoimmune disorders etc… The area labeled calcification occurs as a secondary result of the initial soft plaque, as the plaque becomes more chronic it actually calcifies on its own. The calcification process is more of a result of the chronic nature of the plaque, and less impacted by the levels of calcium in the bloodstream, eventhough excess circulating calcium does play a role.

So…. As you can see from the calcified artery, the amount of occlusion is not dependent ONLY on the amount of calcium in the plaque, thus the reason for the lack of ability to give direct numbers when it comes to calcium score and arterial occlusion. Yes, the higher the calcium score, the assumption can be made the higher the occlusion of the artery, and additional testing would be needed in some cases. However, everyone is different, every plaque is different with different proportions of Calcium (Hard part of the plaque) vs. the soft part of the plaque.

Coronary CT Angiogram OR Cardiac Cath would be recommended in those individuals who are symptomatic and / or has high cardiovascular risk factors, to determine the extent of coronary artery obstruction.

BOTTOM LINE —– PREVENTION — LOWER YOUR INFLAMMATION —

Yes calcium metabolism is important, however less important than risk factors that involve development of the soft part of the plaque— THE ROOT CAUSE- Inflammation and Oxidation at the endothelial surface, no matter what the inciting agent is that causes the initial disruption to the endothelial lining of the artery. Without soft plaque, calcium has no area to deposit or accumulate.

Curcu-Meric 975mg – Extremely Preventative for Many disorders especially Cardiovascular Disease. LOWER YOUR INTRA-ARTERIAL INFLAMMATION AND OXIDATIVE STRESS !

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